Epothilone

  • Anti-cancer drug. Same binding site as [[Paclitaxel taxol]]
  • Macrolide natural product
  • Thiazol

[! tip]- Heterocyclic nomenclature Remember common five member ring nomenclature:

  • completely unsaturated: pyrrol, furan, imidazol, oxazol, thiophene, thiazol
  • partially saturated: pyrroline, oxazolin, thiazolin
  • completely saturated: pyrrolidine, oxazolidine, thiazolidine

Nicolau synthesis

Nicolau synthesis ___

Biosynthesis

biosynthesis