Nitrosoureas

Cell cycle non-specific chemotherapy.

Carmustine

carmustine|200

Lomustine

lomustine|200

  • highly lipophyllic
  • easily crosses blood-brain barrier
  • treatment of brain tumours*

Dacarbazine

Temozolamide

Procarbazine

Questions

  1. What is the main distincting between covalent action of cis-platin and mustards?
  2. Give examples of cell cycle specific chemotherapy agents.