Tamoxifen binding to estrogen receptor.

PDB molecule of the month Estrogen Receptor

Estrogen receptors are nuclear receptors.

PDB: 1qku estradiol bound to estrogen receptor PDB: 3ert tamoxifen bound to estrogen receptor


  1. Identify the common residues with which estraiol and tamoxifen interact.
  2. Overlay the structures of estradiol bound and tamoxifen bound to the receptor.