Tamoxifen

Tamoxifen binding to estrogen receptor.

PDB molecule of the month Estrogen Receptor

Estrogen receptors are nuclear receptors.

PDB: 1qku estradiol bound to estrogen receptor PDB: 3ert tamoxifen bound to estrogen receptor

Questions

1. Identify the common residues with which estraiol and tamoxifen interact.
2. Overlay the structures of estradiol bound and tamoxifen bound to the receptor.